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2019 – 2021

94. Synthesis of α-Quaternary Bicyclo[1.1.1]pentanes through Synergistic Organophotoredox and Hydrogen Atom Transfer Catalysis


J. Nugent, A.J. Sterling, N. Frank, J.J. Mousseau, E.A. Anderson*

Org. Lett. 2021, 23, 8628–8633


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93. Beyond strain release: Delocalisation-enabled organic reactivity


A. Sterling, R. Smith, E. Anderson, F. Duarte

ChemRxiv, 2021



92. Synthesis and Applications of Polysubstituted Bicyclo[1.1.0]butanes


R.E. McNamee, A.L. Thompson, E.A. Anderson*


J. Am. Chem. Soc.2021, 143, 50, 21246–21251


91. Synthesis of the C1–C27 Fragment of Stambomycin D Validates Modular Polyketide Synthase-Based Stereochemical Assignments


J. Lim, V. Chintalapudi, H.G. Gudmundsson, M. Tran, A. Bernasconi, A. Blanco, L. Song, G.L. Challis, and E.A. Anderson*


Org. Lett.2021, 23, 19, 7439–7444



90. Regio- and stereoselective addition of Brønsted acids to yndiamides: Synthesis of N,O,N- and N,S,N-trisubstituted ketene acetals


O.L Garry, S.J. Mansfield, and E.A. Anderson*


Synthesis2021, 53, 22, 4221-4230



89. Synthesis of Polysubstituted Fused Pyrroles by Gold-Catalyzed Cycloisomerization/1,2-Sulfonyl Migration of Yndiamides


P.J. Smith, Y. Jiang, Z. Tong, H.D. Pickford, K.E. Christensen, J. Nugent, and E.A. Anderson*


Org. Lett.2021, 23, 6547–6552,



88. Recent progress in the total synthesis of pyrrole-containing natural products (2011–2020)


N. Singh,‡ S. Singh,‡ S. Kohli, A. Singh, H. Asiki, G. Rathee, R. Chandra,* and E.A. Anderson*


Org. Chem. Front.2021, 8, 5550-5573



87. Twofold Radical-Based Synthesis of N,C-Difunctionalized Bicyclo[1.1.1]pentanes


H. D. Pickford, J. Nugent, B. Owen, J. J. Mousseau, R. C. Smith and 

E.A. Anderson*


J. Am. Chem. Soc.2021143, 9729–9736,



86. Au(I)-Catalyzed Oxidative Functionalization of Yndiamides


Z. Tong, O. L. Garry, P. J. Smith, Y. Jiang, S. J. Mansfield and E. A. Anderson*


Org. Lett.2021, 23, 4888–4892,



85. Synthesis of 1,3-Disubstituted Bicyclo[1.1.0]butanes via Directed Bridgehead Functionalization


R. McNamee, M. M. Haugland, J. Nugent, R. Chan, K. Christensen and E. A. Anderson*


Chem. Sci.2021, 127480–7485,



84. Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria


A. G. Tempone,* P. Pieper, S. E. T. Borborema, F. Thevenard, J. H. G. Lago, S. L. Croft,* E. A. Anderson*


Nat. Prod. Rep.2021, 38, 2214-2235


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83. Direct catalytic asymmetric synthesis of α-chiral bicyclo[1.1.1]pentanes


M. L. J. Wong, A. J. Sterling, J. J. Mousseau, F. Duarte,* E. A. Anderson*


Nat. Commun.2021, 12, 1644,


Blog post:

Highlighted in SYNFORM: 10.1055/s-0040-1720531


82. Advances in polycyclization cascades in natural product synthesis


Y. Jiang, R. E. McNamee, P. J. Smith, A. Sozanschi, Z. Tong,

E. A. Anderson*


Chem. Soc. Rev., 2021, 50, 58–71



81. Synthesis and Structure–Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi


C. E. Sear, P. Pieper, M. Amaral, M. M. Romanelli, T. A. Costa-Silva, M. M. Haugland, J. A. Tate, J. H. G. Lago, A. G. Tempone*, E. A. Anderson*


ACS Infect. Dis., 2020, 6, 2872–2878

doi: 10.1021/acsinfecdis.0c00523


80. Site-Selective C–H Benzylation of Alkanes with N-Triftosylhydrazones Leading to Alkyl Aromatics


Z. Liu, S. Cao, W. Yu, J. Wu, F. Yi, E. A. Anderson*, X. Bi*


Chem, 2020, 6, 2110–2124, 

doi: 10.1016/j.chempr.2020.06.031


79. Copper-Catalyzed Intramolecular C–H Alkoxylation of Diaryltriazoles: Synthesis of Tricyclic Triazole Benzoxazines


X. Ma, H. Li, H. Xin, W. Du, E. A. Anderson*, X. Dong*, Y. Jiang*


Org. Lett., 2020, 22, 5320–5325 

doi: 10.1021/acs.orglett.0c01517


78. Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design


F. S. de Sousa, J. L. Baldim, R. A. Azevedo, C. R. Figueiredo, P. Pieper,

C. E. Sear, E. A. Anderson, J. H. G. Lago


Bioorg. Med. Chem. Lett., 2020, 30, 127349,

doi: 10.1016/j.bmcl.2020.127349

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77. Synthesis of All-carbon Disubstituted Bicyclo[1.1.1]pentanes by Iron-Catalyzed Kumada Cross-Coupling


J. Nugent,‡ B. R. Shire,‡, D. F. J. Caputo, H. D. Pickford, F. Nightingale,

I. T. T. Houlsby, J. J. Mousseau,  E. A. Anderson

equal author contribution


Article: Angew. Chem. Int. Ed., 202059, 11866–11870

 doi: 10.1002/anie.202004090

Featured in: Org. Process Res. Dev., 2020, 24, 8, 1351–1363

doi: 10.1021/acs.oprd.0c00344


76. Rationalizing the diverse reactivity of [1.1.1]propellane through 𝜎-𝜋-delocalization


A. J. Sterling, A. B. Dürr, R. C. Smith, E. A. Anderson, F. Duarte


Chem. Sci., 2020, 11, 4895–4903 

doi: 10.1039/D0SC01386B

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75. 2′-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis


J. S. Hardwick, M. M. Haugland, A. H. El-Sagheer, D. Ptchelkine, 

F. R. Beierlein,  A. N. Lane,  T. Brown,  J. E. Lovett,  E. A. Anderson


Nucleic Acids Research, 202048, 2830–2840. 



74. A Modular, Enantioselective Synthesis of Resolvins D3, E1, and Hybrids


F. Urbitsch, B. L. Elbert, J. Llaveria, P. E. Streatfeild, E. A. Anderson


Org. Lett., 202022, 1510–1515. 

doi: 10.1021/acs.orglett.0c00089


73. Enantioselective synthesis and anti-parasitic properties of aporphine natural products


P. Pieper, E. McHugh, M. Amaral, A. G.Tempone, E. A.Anderson


Tetrahedron., 2019, 76, 130814. 

doi: 10.1016/j.tet.2019.130814

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72. Synthesis of Cyclic Alkenyl Dimethylsiloxanes from Alkynyl Benzyldimethylsilanes and Application in Polyene Synthesis


H. G. Gudmundsson, C. J. Kuper, D. Cornut, F. Urbitsch, B. L. Elbert,

E. A. Anderson


J. Org. Chem., 201984, 14868-14882. 

doi: 10.1021/acs.joc.9b01664

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71. Convergent Total Syntheses of (–)-Rubriflordilactone B and (–)-pseudo-Rubriflordilactone B


M. Mohammad, V. Chintalapudi, J. M. Carney, S. J. Mansfield, P. Sanderson, K. E. Christensen, E. A. Anderson


Angew. Chem. Int. Ed., 201958, 18177–18181. 

doi: 10.1002/anie.201908917

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70. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi


D. D. Ferreira, F. S. Sousa, T. A. Costa-Silva, J. Q. Reimão, A. C. Torrecilhas, D. M. Johns, C. E. Sear, K. M. Honorio, J. H. G. Lago, E. A. Anderson, A. G. Tempone


Eur. J. Med. Chem.2019, 176, 162-174. 

doi: 10.1016/j.ejmech.2019.05.001

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69. A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division


M. Amaral, F. S. de Sousa, T. A. Costa Silva, A. Jimenez G. Junior, N. N. Taniwaki, D. M. Johns, J. H. G. Lago, E. A. Anderson & A. G. Tempone


Scientific Reports2019, 6, 6114.

doi: 10.1038/s41598-019-42273-z

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68. Silver-Catalyzed C- to N-Center Remote Arene Migration


Y. Ning, A. Mekareeya, K. R. Babu, E. A. Anderson and X. Bi


ACS Catalysis2019, 9, 4203-4210. 

doi: 10.1021/acscatal.9b00500


67. A General Route to Bicyclo[1.1.1]pentanes through Photoredox Catalysis.
J. Nugent,* C. Arroniz,* B. R. Shire, A. J. Sterling, H. D. Pickford, M. L. J. Wong,  S. J. Mansfield, D. F. J. Caputo, B. Owen,  J. J. Mousseau, F. Duarte and E. A. Anderson
*equal author contribution
ACS Catalysis2019, 9, 9568-9574.
doi: 10.1021/acscatal.9b03190

66. A General Copper-Catalyzed Synthesis of Ynamides from 1,2-Dichloroenamides.
S. J. Mansfield, R. C. Smith, J. R. J. Yong, O. L. Garry, and E. A. Anderson
Org. Lett., 2019, 21, 2918-2922. 
doi: 10.1021/acs.orglett.9b00971.

65. Synthesis of Enantioenriched α-Chiral Bicyclo[1.1.1]pentanes.
M. L. J. Wong, J. J. Mousseau, S. J. Mansfield and E. A. Anderson.
Org. Lett., 2019, 21, 2408-2411. 
doi: 10.1021/acs.orglett.9b00691.

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64. Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides. 
Y. Hou, J. Ma, H. Yang, E. A. Anderson, A. Whiting and N. Wu. 
Chem. Commun., 2019, 55, 3733-3736. 
doi: 10.1039/C9CC00537D.


63. Direct Transformation of Terminal Alkynes into Amidines by a Silver-Catalyzed Four-Component Reaction. 
B. Liu, Y. Ning, M. Virelli, G. Zanoni, E. A. Anderson and X. Bi. 
J. Am. Chem. Soc., 2019, 141, 1593-1598.
doi: 10.1021/jacs.8b11039.

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62. Use of trifluoroacetaldehyde N-tfsylhydrazone as a trifluorodiazoethane surrogate and its synthetic applications.

X. Zhang, Z. Liu, X. Yang, Y. Dong, M. Virelli, G. Zanoni, E. A. Anderson and X. Bi. 
Nature Commun., 2019, 10, 284
doi: 10.1038/s41467-018-08253-z.


61. Four Step Total Synthesis of an H3 Receptor Antagonist Using Only Tools Found in a Typical Teaching Laboratory.

C. J. Smith, S. J. Mansfield, E. A. Anderson and J. W. Burton. 
J. Chem. Educ., 2019, 96, 137-142
doi: 10.1021/acs.jchemed.7b00982.

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