2022-2025| Ed Anderson Group

2022 – 2025

121. Synthesis of bicyclo[3.1.1]heptanes, meta‑substituted arene isosteres, from [3.1.1]propellane
Bhaskar Paul, Ayan Dasgupta, Nils Frank,
Jeremy Nugent & Edward A. Anderson

Nat. Protoc., 2025, 20, 2056–2082
doi:10.1038/s41596‑024‑01109‑5

120. Hetero[3.1.1]propellanes
Rebecca I. Revie, Ayan Dasgupta, Yasmine Biddick, Kirsten E. Christensen, Russell C. Smith, Edward A. Anderson

ChemRxiv, 2024, preprint posted 31 December; doi:10.26434/chemrxiv‑2024‑tnx0l

119. Asymmetric dearomative single‑atom skeletal editing of indoles and pyrroles
Xiaolong Zhang, Qingmin Song, Shaopeng Liu, Paramasivam Sivaguru, Zhaohong Liu, Yong Yang, Yongyue Ning, Edward A. Anderson,
Graham de Ruiter, Xihe Bi

Nat. Chem., 2025, 17(2), 215–225;
doi:10.1038/s41557‑024‑01680‑0

118. Halogencarbene‑free Ciamician‑Dennstedt single‑atom skeletal editing
Shaopeng Liu, Yong Yang, Qingmin Song, Zhaohong Liu,
Paramasivam Sivaguru, Yifan Zhang, Graham de Ruiter,
Edward A. Anderson, Xihe Bi

Nat. Commun., 2024, 15(1), 9998;
doi:10.1038/s41467‑024‑54379‑8

117. Collective asymmetric synthesis of the Strychnos alkaloids via thiophene S,S‑dioxide cycloaddition cascades
Kun Ho (Kenny) Park, Jisook Park, Nils Frank, Hanwen Zhang,
Fernanda Duarte, Edward A. Anderson

ChemRxiv, 2024, preprint posted 15 November; doi:10.26434/chemrxiv‑2024‑tk00d

116. Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis—mechanism of action and in vivo pharmacokinetic studies
Maiara Amaral, Maiara M. Romanelli, Hannah Asiki, Joana Bicker,
Daniela P. Lage, Camila S. Freitas, Noemi N. Taniwaki, Joao H. G. Lago, Eliane A. F. Coelho, Ana Fortuna, Edward A. Anderson, Andre G. Tempone

Antimicrob. Agents Chemother., 2024, 68(11), e00831‑24;
doi:10.1128/aac.00831‑24

115. Beyond Strain Release: Delocalization‑Enabled Organic Reactivity
Alistair J. Sterling, Russell C. Smith, Edward A. Anderson, Fernanda Duarte

J. Org. Chem., 2024, 89(14), 9979–9989;
doi:10.1021/acs.joc.4c00857

114. Intravenous iron therapy results in rapid and sustained rise in myocardial iron content through a novel pathway

Mayra Vera‑Aviles, Syeeda Nashitha Kabir, Akshay Shah, Paolo Polzella, Dillon Yee Lim, Poppy Buckley, Charlotte Ball, Dorine Swinkels,

Hanke Matlung, Colin Blans, Philip Holdship, Jeremy Nugent,

Edward A. Anderson, Michael Desborough, Stefan Piechnik,

Vanessa Ferreira, Samira Lakhal‑Littleton

Eur. Heart J., 2024, 45(42), 4497–4508;
doi:10.1093/eurheartj/ehae359

113. Sα-Amino bicycloalkylation through organophotoredox catalysis

Jeremy Nugent, Adrián López-Francés, Alistair J. Sterling, Min Yi Tay, Nils Frank, James J. Mousseau, Fernanda Duarte and Edward A. Anderson

Chem. Sci., 2024, Advance Article

https://doi.org/10.1039/D4SC01368A

112. Synthesis and Evaluation of (Bis)benzyltetrahydroisoquinoline Alkaloids as Antiparasitic Agents

Ana Sozanschi, Hannah Asiki, Maiara Amaral, Erica V. de Castro Levatti, Andre G. Tempone, Richard J. Wheeler, and Edward A. Anderson

JACS Au. 2024 Article ASAP

111. Synthesis of Heterocycle-Substituted Bicyclo[3.1.1]heptanes and Aza-bicyclo[3.1.1]heptanes via Photocatalytic Minisci Reaction

Rebecca I. Revie, Benjamin J. Whitaker, Bhaskar Paul, Russell C. Smith, and Edward A. Anderson*

Org. Lett. 2024

https://doi.org/10.1021/acs.orglett.3c03684

110. Taming non-classical carbocations to control small ring reactivity

Ryan E. McNamee, Nils Frank, Kirsten E. Christensen, Fernanda Duarte, Edward A. Anderson

Sci. Adv. 2024, 10

109. Stereoselective Alder-Ene Reactions of Bicyclo[1.1.0]butanes: Facile Synthesis of Cyclopropyl- and Aryl-Substituted Cyclobutenes

Ayan Dasgupta, Subrata Bhattacharjee, Zixuan Tong, Avishek Guin, Ryan E. McNamee, Kirsten E. Christensen, Akkattu T. Biju, Edward A. Anderson

J. Am. Chem. Soc. 2024, 146(1), 1196–1203

https://doi.org/10.1021/jacs.3c13080

108. Bridge Cross-Coupling of Bicyclo[1.1.0]butanes

Ryan E. McNamee, Ayan Dasgupta, Kirsten E. Christensen, Edward A. Anderson.

Org. Lett. 2024, 26(1), 360–364

https://doi.org/10.1021/acs.orglett.3c04030

107. Gold-Catalyzed Cyclization of Yndiamides with Isoxazoles via α-Imino Gold Fischer Carbenes

Zixuan Tong, Philip J. Smith, Helena D. Pickford, Kirsten E. Christensen, Edward A. Anderson

Chem. Eur. J. 2023 e202302821

https://doi.org/10.1002/chem.202302821

106. Sequencing palladium-catalyzed cycloisomerization cascades in a synthesis of the gelsemine core

Guoduan Liang, Edward A. Anderson

Chem. Sci. 2023, 14(25), 6970–6974

https://doi.org/10.1039/D3SC01353G

105. Synthetic Study toward Triterpenes from the Schisandraceae Family of Natural Products

Petar Kravljanac, Edward A. Anderson

Molecules 2023, 28(11), 4468

https://doi.org/10.3390/molecules28114468

104. Biological Activity and Structure−Activity Relationship of Dehydrodieugenol B Analogues against Visceral Leishmaniasis

Marta Amaral, Hassina Asiki, Catherine E. Sear, Sunil Singh, Peter Pieper, Marit M. Haugland, Edward A. Anderson, André G. Tempone

RSC Med. Chem. 2023, 14, 1344-1350

103. Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes

Benjamin R. Shire, Edward A. Anderson.

JACS Au 2023, 3(6), 1539–1553

https://doi.org/10.1021/jacsau.3c00014

102. Chemoselective carbene insertion into the N−H bonds of NH3·H2O

Zhihao Liu, Yuchao Yang, Qi Song, Lei Li, Gianfranco Zanoni, Shuai Liu, Mengjie Xiang, Edward A. Anderson, Xiaoyu Bi

Nat. Commun., 2022, 13(1), 7649

doi:10.1038/s41467-022-35394-z

99. Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane

Nils Frank, Jeremy Nugent, Benjamin R. Shire, Helena Pickford, Paul Rabe, Alexander Sterling, Theodoros Zarganes‑Tzitzikas, Thomas Grimes, Andrew Thompson, Robert Smith, Catherine Schofield, Paul Brennan, Fernanda Duarte, Edward A. Anderson

Nature 2022, 611, 721–726

https://doi.org/10.1038/s41586-022-05290-z

100. Rapid and scalable halosulfonylation of strain-release reagents

Helena Pickford, Viktoriia Ripenko, Ryan E. McNamee, Sergii Holovchuk, Andrew Thompson, Richard Smith, Petro Mykhailiuk, Edward A. Anderson

Angew. Chem. Int. Ed. 2023, 62, e202213508;

Angew. Chem. 2023, 135, e202213508

doi: https://doi.org/10.1002/anie.202213508

101. Rhodium-Catalyzed [2 + 2 + 2] Cyclotrimerizations of Yndiamides with Alkynes

Philip J. Smith, Zixuan Tong, James Ragus, Pieter Solon, Kevin W. Shimkin, Edward A. Anderson

Org. Lett. 2022, 24 (41), 7522–7526

https://doi.org/10.1021/acs.orglett.2c02770

98. Collective Synthesis of Illudalane Sesquiterpenes via Cascade Inverse Electron Demand (4 + 2) Cycloadditions of Thiophene S, S-Dioxides

Kang‑Hui Kim Park, Nils Frank, Fernanda Duarte, Edward A. Anderson

J. Am. Chem. Soc. 2022,144 (22), 10017–10024

doi: 10.1021/jacs.2c03304

97. Carbodefluorination of fluoroalkyl ketones via a carbene-initiated rearrangement strategy

Lei Li, Xiaohan Zhang, Yang Ning, Xiaoyu Zhang, Bing Liu, Zhi‑gang Zhang, Palani Sivaguru, Gianfranco Zanoni, Shuo Li, Edward A. Anderson, Xiaoyu Bi

Nat Commun. 2022, 13, 4280

https://doi.org/10.1038/s41467-022-31976-z

95. Synthesis of the C50 diastereomers of the C33-C51 fragment of stambomycin D

Yongchen Wang, Venkaiah Chintalapudi, Haraldur G. Gudmundsson, Gregory L. Challis, Edward A. Anderson

Org. Chem. Front., 2022, 9, 445-449

https://doi.org/10.1039/D1QO01635K

96. Silver-catalyzed site-selective C(sp3)−H benzylation of ethers with N-triftosylhydrazones

Zhihao Liu, Huirong Wang, Palani Sivaguru, Stephen P. Nolan, Qi Song, Wei Yu, Xiaobo Jiang, Edward A. Anderson, Xiaoyu Bi