DR JEREMY NUGENT
I come from Canberra, the capital city of Australia. I received my Ph.D. from the Australian National University under the guidance of Prof. Martin Banwell where I worked on new methodology for natural product synthesis. After a further year at the ANU as a postdoctoral fellow, I sought warmer climes and moved to the U.K. In the Anderson group, my research is concerned with the development of new methodology to install the bicyclo[1.1.1]pentane ring system into complex molecules.
DR NICHOLAS TAPPIN
Anti-Leishmaniasis Natural Products
I was born and bred 10 km east of Manchester in the foothills of the Peak District in the UK. I obtained my M.Sci. in 2009 from Queens’ College, University of Cambridge, after studies in flow chemistry at the Innovative Technology Centre under the direction of Prof. Steven V. Ley. In 2019 I received my doctorate (summa cum laude) on the subject of 1-boryl radicals under the tutelage of Prof. Philippe Renaud and continued there, at the University of Bern, Switzerland, for short postdoctoral studies on new radical initiation strategies and radical chain reactions involving organoboron. I joined the Anderson Group on a Swiss National Science Foundation fellowship to work on the total synthesis of anti-leishmaniasis natural products.
4th Year (Total Synthesis)
I was born and raised in the suburbs of Detroit, Michigan, U.S.A.. I completed two Bachelor of Science degrees from Michigan State University, one in chemistry and the other in biochemistry and molecular biology. During my tenure at Michigan State University, I worked in Prof Babak Borhan’s lab investigating a one-pot synthesis of highly functionalized bicyclic piperidines using the hetero-Diels-Alder reaction, developed diastereoselective halogenated spiroketals, and assisted in creating a halenium affinity scale. I completed my senior thesis under the supervision of Prof Honggao Yan, studying the Michaelis-Menten kinetics of enzymes by using site-directed mutagenesis. Upon graduation, I proceeded to work several years in various fields of the pharmaceutical industry for a couple different companies doing biochemical testing and as a research scientist in analytical development, solid-state chemistry and crystallography. In the Anderson group I am working towards the total synthesis of heronamide F. Outside the lab, I currently am the president of Science Innovation Union, a graduate and post-graduate student led non-profit organisation helping scientist learn to translate their research, and I enjoy fishing, hiking, camping, cooking, and like to stay in shape by playing most sports.
2nd Year (Ynamides & Yndiamides)
I am from Newcastle upon Tyne and completed my MChem at the University of Oxford; in my Part II year I worked for Professor Tim Donohoe on iridium-catalysed reductive functionalisation of pyridinium salts. I am part of the SBM CDT, and having completed a rotation project on rhodium-catalysed cycloisomerisations of ynamide-vinylcyclopropanes, I am now working on a project to explore the regioselective reactivity of yndiamides. Outside of the lab I am very involved with my church and also enjoy hill walking and various sports.
2nd Year (Bicyclopentane Methodology)
Originally from Tyrone, Northern Ireland, Ryan has completed his MSci degree in Medicinal Chemistry at Queen's University Belfast. In his final year in the Knipe group, Ryan worked on the catalytic asymmetric synthesis of spirocyclic oxindoles. In the year preceding his final year, he also undertook a one-year industrial placement at GlaxoSmithKline synthesising compounds for the potential treatment of respiratory diseases. His current interests primarily lie in the synthesis of strained rings, and aside from chemistry, he enjoys dancing and many outdoor activities.
2nd Year (Anti-Leishmaniasis Natural Products)
I was born and raised in Brasov, Romania, and completed my Medicinal Chemistry & Chemical Biology degree at University College Dublin (UCD), Dublin, Republic of Ireland. My final year project involved the synthesis of cyclopentenone prostaglandin analogues and their corresponding Cysteine adducts. Following their synthesis, novel compounds were investigated for their biological activity. I have also worked in Dr. E. McGarrigle’s Lab in the Centre for Synthesis and Chemical Biology, UCD, for which I was awarded an Undergraduate Bursary by the Royal Society of Chemistry. The project I was working on involved probing the reactivity and stereoselectivity in organocatalytic glycosylations. Outside the lab I enjoy baking, ballroom dancing and hiking.
2nd Year (Yndiamides)
I was born and raised in Beijing, but I acquired my BSc in Chemistry from City University of Hong Kong. I worked on platinum-based anticancer drugs in Dr. Guangyu Zhu group for my undergraduate final year project. My project now in EAA group aims to explore the stereoselective reactivity of yndiamides. Aside from chemistry, I enjoy cooking and traveling. I am also a fan of traditional Chinese performances, especially crosstalk.
4th Year (Bicyclopentane Methodology)
I come from a village called Farnham Common in South Bucks, and completed my MChem degree at Exeter College, University of Oxford. My part II project was supervised by Professors Jeremy Robertson and Luet Wong, working towards the total synthesis of Trigoxyphins K and L using cytochrome P450 enzymes as a tool for late stage functionalisation. I have now joined the Anderson group for my DPhil project, investigating new methodologies to form functionalized bicyclo[1.1.1]-pentanes as a bioisostere for pharmaceuticals. Aside from Chemistry, I enjoy many outdoors activities including skiing, rowing and cycling, and coming home to cup of tea or a pint in the pub.
4th Year (Bicyclopentane Methodology)
I’m from a small village called Whaley Bridge in the Peak District, and completed my MChem degree at Pembroke College, University of Oxford. I did my Part II project under the supervision of Prof. Ed Anderson, investigating enynamide cycloisomerisations with applications towards the synthesis of Gelsemine. I have now rejoined the group for my DPhil, and I am working on developing new methodologies around bicyclo[1.1.1]pentanes – a bioisostere for 1,4-substituted arenes in drug development. Outside the lab I enjoy cooking, American football, horror movies and going to the pub.
4th Year (Physical Organic Chemistry)
I'm from the seaside town of Weymouth on the South coast of the UK. I completed my Masters Degree in Ed's group, working on the total synthesis of polyketide natural products. I have also worked with Prof Erick Carreira at ETH Zürich on the application of asymmetric catalysis to total synthesis. My research focuses on the reactivity of small strained rings, under the co-supervision of Prof. Fernanda Duarte. Outside the lab, I enjoy cycling, running, music and cooking.
3rd Year (Total Synthesis)
I completed my BSc at Nanyang Technological University, Singapore. After graduation, I spent a year at Solvay, then moved on to the Institute of Chemical and Engineering Sciences, A*STAR. Besides chemistry, I enjoy playing the violin, sewing, and spending time with friends.
3rd Year (Total Synthesis)
I am Yongchen, coming from Xuzhou, Jiangsu province, China. I completed my B.S.degree in Chemistry at Nanjing University of Technology in 2018. During my last year of undergraduate study, I worked on the preparation of kaolin/organic intercalated composites and finished my dissertation which was on the preparation of kaolin/organic intercalated composite and its intercalation analysis. Now I am engaged in the research of total synthesis of natural products in the Anderson group. Outside the lab, I am fond of watching films, travelling and especially cooking various Chinese dishes.
1st Year (Total Synthesis)
My name is Guoduan Liang who is from Fujian Province, China. I am an active and diligent person and very interested in total synthesis and transition metal catalysis. I obtained my Master degree in ShenYang Pharmaceutical University in China, studying on the synthesis of spiro[indoline-3,4’-piperidine] via silver-catalyzed tandem cyclizations of tryptamine-ynesulfonamides controlled by ligand under the supervision of Prof. Yongxiang Liu. Now I focus on the total synthesis in the EAA group. Outside the lab, I love sports and reading novels.
Kun Ho (Kenny) Park
1st Year (Total Synthesis)
I was born in South Korea; however, I moved during childhood to the United States. I obtained a Bachelor of Science degree from University of California at Berkeley. Upon completion, I moved back to my home country for graduate work and also fulfill my military service. During my Masters study, under the guidance of Prof. David Yu-Kai Chen, I worked on the total synthesis of various morphinan family and haouamine A. In continuing my journey as a synthetic chemist, I’m currently involved in total synthesis of new class compounds in EAA group. Outside the lab, I enjoy working out and watching youtube videos.
1st Year (Anti-Leishmaniasis Natural Products)
I am originally from Arua, a small town in northern Uganda. I completed my MChem at the University of Oxford on the synthesis of biaryl ether anti-parasitic natural products under the supervision of Prof. Ed Anderson. I am now on the Chemistry in Cells programme and have returned to the group under the co-supervision of Dr. Richard Wheeler, to investigate the mechanism of action of these compounds in trypanosomatids. I have previously worked for Prof. Barry Potter synthesising novel difluorinated anti-cancer compounds, and spent a year working at the Institute of Cancer Research in London. Outside of the lab I enjoy going on walks, painting and rowing.
CDT ROTATION STUDENTS
SBM Rotation (Bicyclopentane Methodology)
1st Year (Total Synthesis)
I come from Belgrade, the capital of Serbia. During my undergraduate studies in Chemistry at the University of Belgrade, I worked on a total synthesis of an alkaloid under the supervision of professors F. Bihelovic and Z. Ferjancic. Currently, I am doing a DPhil in the Prof. E. Anderson group, where I am also working on a total synthesis, but this time my target is switched to terpenoids. Outside the lab, I enjoy delicious food from my college and listening to music.
PART II / MASTERS STUDENTS
Bicyclopentane Methodology & Computation
I am from Germany and completed my undergraduate (Bachelor) degree there at the Karlsruhe Institut of Technology (KIT). During a summer internship, I worked in the group of Prof. Ritter at the Max-Planck-Institute for Coal Research on the reactivity Thianthrenium-salts. Besides getting my hands on "real" molecules I am eager to grasp them better in silico. Therefore, I finalised my undergraduate degree with a project in the theoretical-chemistry group of Dr Fink and Prof. Klopper. During my "Master by Research" years in the Ed Anderson group, I hope to find some interesting reactivity of the propellane-family. Also, I am trying to study them with the help of computational chemistry supported by the Prof. Duarte group. When not in front of a fume hood or a computer, I like to go out jogging or watching films.
Part II (Bicyclopentane Methodology)
I was born in Hong Kong but moved to the UK when I was 5 and have lived here ever since. I started my MChem at Balliol College, University of Oxford in 2017 and I’m currently in my Part II year with the Ed Anderson Group. In my current project, I am aiming to make bicyclopentane analogues of the ‘Sartan’ family of hypertension pharmaceuticals using methodologies developed by the group. I also did a cardiac regeneration summer project after my 2nd Year with the Angela Russell Group. When I’m not in the lab, I enjoy playing Dungeons & Dragons, reading Sci-Fi novels, cooking and going for walks in Uni Parks.
Part II (Bicyclopentane Mechanistic Studies)
I come from a city called Szczecin in Poland, and I am completing my MChem degree at Somerville College. I have previously worked with Prof. J. Sosnicki on addition of magnesium “ate” complexes to 2-(thio)pyridones. For my Part II project, I am working to synthesize a range of [1.1.1]-propellane mechanistic probes to better understand it's reactivity. Outside the lab I tutor for Chemistry Olympiad. I enjoy cycle trips, cooking, a cup of nice tea, and a good drink.
Part II (Total Synthesis)
I am from Wiltshire and I am currently in my fourth year studying MChem Chemistry at Brasenose College. My Part II project consists of developing novel routes in the synthesis of stambomycin D fragments, building upon current methods the group use. Outside the lab I enjoy listening to music and podcasts, cooking, and watching films!
Floyd arrived with us in late October 2014 from the Amazon. He astutely supervises the group in all things chemistry, whilst adding a dash of pink to the office area. In his free time Floyd enjoys wading in the Isis and sunning himself on the beach with beers.